Bioactivity | FFN270 hydrochloride, a fluorescent tracer of norepinephrine, is a fluorescent substrate of the norepinephrine and vesicular monoamine transporters. FFN270 hydrochloride exhibits two resolved absorption/excitation maxima depending on solvent pH (FFN270 ex: 320 nm or 365 nm, em: 475 nm) and can function as ratiometric fluorescent pH-sensors[1]. |
Invitro | FFN270 enables both an examination of noradrenergic microanatomy and an observation of synaptic activity in the cortex of intact neuronal circuits in vivo[1]. |
Name | FFN270 hydrochloride |
CAS | 2341841-05-0 |
Formula | C11H11ClFNO3 |
Molar Mass | 259.66 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | -20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Reference | [1]. Matthew Dunn, et al. Designing a norepinephrine optical tracer for imaging individual noradrenergic synapses and their activity in vivo. Nat Commun. 2018 Jul 19;9(1):2838. |