| Bioactivity | Etoxadrol (CL-1848C) is a potent N-methyl-D-aspartic acid (NMDA) antagonist with high affinity. Etoxadrol can be used for anaesthetic research[1]. |
| Target | NMDA |
| In Vivo | Etoxadrol (CL-1848C) (100.0 mg/kg; i.h.; once) produces marked stimulation and ataxia in mice[2].Etoxadrol (0-20 mg/kg; i.v.; once) decreases brain monoamine concentrations after 4 h injection[3]. Animal Model: |
| Name | Etoxadrol |
| CAS | 28189-85-7 |
| Formula | C16H23NO2 |
| Molar Mass | 261.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. A Thurkauf, et al. Synthesis, absolute configuration, and molecular modeling study of etoxadrol, a potent phencyclidine-like agonist. J Med Chem. 1988 Dec;31(12):2257-63. [2]. A H Tang, et al. Analgetic activities of etoxadrol in the rhesus monkey and in mice. Anesth Analg. 1973 Jul-Aug;52(4):577-83. [3]. Y F Sung, et al. Effects of intravenous anesthetics on brain monoamines in the rat. Anesthesiology. 1973 Nov;39(5):478-87. |