| Bioactivity | Ethylenethiourea is a degradation product of the ethylenebisthiocarbamate group of fungicides. Ethylenethiourea is tumorigenic and teratogenic. Ethylenethiourea is orally active[1][2]. | ||||||||||||
| Invitro | Ethylenethiourea is stable at elevated temperature over a wide pH range[1]. | ||||||||||||
| In Vivo | Ethylenethiourea (10-80 mg/kg; p.o.) is teratogenic in rats[1].Ethylenethiourea (5-500 ppm; in the diet; 12 month) induces thyroid carcinomas in rats[2]. Animal Model: | ||||||||||||
| Name | Ethylenethiourea | ||||||||||||
| CAS | 96-45-7 | ||||||||||||
| Formula | C3H6N2S | ||||||||||||
| Molar Mass | 102.16 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Khera KS. Ethylenethiourea: teratogenicity study in rats and rabbits. Teratology. 1973 Jun;7(3):243-52. [2]. Graham SL, et al. Effects of one-year administration of ethylenethiourea upon the thyroid of the rat. J Agric Food Chem. 1973 May-Jun;21(3):324-9. |
Ethylenethiourea
CAS: 96-45-7 F: C3H6N2S W: 102.16
Ethylenethiourea is a degradation product of the ethylenebisthiocarbamate group of fungicides. Ethylenethiourea is tumor
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