| Bioactivity | Ethotoin (Peganone) is an orally active anticonvulsant agent used in epilepsy research, Ethotoin is a hydantoin, similar to phenytoin[1]. |
| In Vivo | Ethotoin (oral gavage; 600 mg/kg; once) results in mild mortality and weight loss of offspring, after dosing on gestational day 18[2]. Animal Model: |
| Name | Ethotoin |
| CAS | 86-35-1 |
| Formula | C11H12N2O2 |
| Molar Mass | 204.23 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Reference | [1]. A S Troupin, et al. Clinical pharmacology of mephenytoin and ethotoin. Ann Neurol. 1979 Nov;6(5):410-4. [2]. D R Minck, et al. Comparison of the behavioral teratogenic potential of phenytoin, mephenytoin, ethotoin, and hydantoin in rats. Teratology. 1991 Apr;43(4):279-93. |