| Bioactivity | Esaprazole (Hexaprazole) is an antiulcer agent that has the effect of promoting the healing of peptic ulcer. Esaprazole can inhibit the secretion of gastric acid and pepsin[1]. |
| In Vivo | Esaprazole (50-450 mg/kg; 十二指肠内给药; 单剂量) 在 Wistar 大鼠中能以剂量依赖方式抑制胃酸和胃蛋白酶的分泌。并且 Esaprazole (25. 50 and 100 mg/kg; 腹腔注射; 单剂量) 也能抑制由贝胆碱 (HY-B0406) (500 μg/kg/h) 引起的酸分泌亢进和由迷走神经刺激引起的胃酸分泌反应[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| CAS | 64204-55-3 |
| Formula | C12H23N3O |
| Molar Mass | 225.33 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Blandizzi C, et al. Gastric antisecretory effects of esaprazole in rats. Digestion. 1992;51(4):226-232. |