| Bioactivity | Equilin (7-Dehydroestrone) is an important member of the large group of oestrogenic substances and is chemically related to menformon (oestrone). Equilin increases the growth of cortical neurons via an NMDA receptor-dependent mechanism[1][2]. | ||||||||||||
| Invitro | Equilin in conjugated equine estrogen increases monocyte-endothelial adhesion via NF-κB signaling[3]. | ||||||||||||
| Name | Equilin | ||||||||||||
| CAS | 474-86-2 | ||||||||||||
| Formula | C18H20O2 | ||||||||||||
| Molar Mass | 268.35 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. David K, et al. Some biological properties of equilin. Biochem J. 1935;29(2):371-377. [2]. Brinton RD, et al. Equilin, a principal component of the estrogen replacement therapy premarin, increases the growth of cortical neurons via an NMDA receptor-dependent mechanism. Exp Neurol. 1997;147(2):211-220. [3]. Ito F, et al. Equilin in conjugated equine estrogen increases monocyte-endothelial adhesion via NF-κB signaling. PLoS One. 2019;14(1):e0211462. Published 2019 Jan 30. |