Bioactivity | Ebiratide (HOE-427 free base) is a synthesized ACTH derivative, which acts directly on the central nervous system and exhibits memory-enhancing efficacy[1]. |
In Vivo | Ebiratide (0.1-30 μg/kg,皮下注射,单剂量) 对电惊厥休克和 Scopolamine (HY-N0296) 诱导的小鼠模型中的记忆障碍具有神经保护功效,并具有抗遗忘功效[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
CAS | 105250-86-0 |
Sequence | {Met(O2)}-Glu-His-Phe-{d-Lys}-{Phe-NH(CH2)8NH2} |
Shortening | {Met(O2)}-EHF-{d-Lys}-{Phe-NH(CH2)8NH2} |
Formula | C48H73N11O10S |
Molar Mass | 996.23 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Hock FJ, et al., Learning and memory processes of an ACTH4-9 analog (ebiratide; Hoe 427) in mice and rats. Peptides. 1988 May-Jun;9(3):575-81. |