| Bioactivity | EDTA-OH is a chelating agent, which forms thermodynamically stable chelates with metal ions like calcium, magnesium, iron, zinc and copper[1]. EDTA-OH exhibits ability of phytoremediation in heavy-metal-contaminated soils[2]. EDTA-OH is able to cross brain-blood barrier[3]. | ||||||||||||
| In Vivo | EDTA-OH (50 mg/kg，腹腔注射 5 天) 可降低血液和大脑中的铝浓度以及大脑的氧化应激。EDTA-OH 可渗透血脑屏障，可作为铝过载的解毒剂[3]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: | ||||||||||||
| CAS | 150-39-0 | ||||||||||||
| Formula | C10H18N2O7 | ||||||||||||
| Molar Mass | 278.26 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Li X, Zhang Z, et al., Complexation of Light Trivalent Lanthanides with N-(2-Hydroxyethyl)ethylenediamine-N,N',N'-triacetic Acid in Aqueous Solutions: Thermodynamic Analysis and Coordination Modes. Inorg Chem. 2019 Nov 18;58(22):15618-15628. [2]. Chen H, et al., EDTA and HEDTA effects on Cd, Cr, and Ni uptake by Helianthus annuus. Chemosphere. 2001 Oct;45(1):21-8. [3]. Flora SJ, et al., Aluminum-induced oxidative stress in rat brain: response to combined administration of citric acid and HEDTA. Comp Biochem Physiol C Toxicol Pharmacol. 2003 Mar;134(3):319-28. |