Didocosahexaenoin_product_DataBase

Bioactivity	Didocosahexaenoin, an omega-3 derivative, is a diglyceride of DHA and can be synthesised from DHA triglycerides. Didocosahexaenoin causes significant loss of mitochondrial membrane potential and induces ROS production. Didocosahexaenoin induces apoptosis. Didocosahexaenoin induces stronger cytotoxicity than DHA in human prostate carcinoma cells[1].
Invitro	二十二碳六烯酸甘油二酯 (10-50 μM; 96 小时) 诱导 PC3 细胞凋亡[1]。二十二碳六烯酸甘油二酯 (1 nM-100 μM; 96 小时) 对人前列腺细胞诱导剂量依赖性细胞毒性[1]。二十二碳六烯酸甘油二酯 (30, 50 μM; 24 小时) 导致线粒体膜电位损失显着增加[1]。 Apoptosis Analysis[1] Cell Line:
Name	Didocosahexaenoin
CAS	124538-05-2
Formula	C25H40O5
Molar Mass	420.58
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Glenn F Robinson, et al. Investigation of the cytotoxicity induced by didocosahexaenoin, an omega 3 derivative, in human prostate carcinoma cell lines. Curr Res Pharmacol Drug Discov. 2022 Jan 19;3:100085.

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