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Didesethyl chloroquine

CAS: 4298-14-0 F: C14H18ClN3 W: 263.77

Didesethyl chloroquine (Bisdesethylchloroquine) is a major metabolite of the antimalarial drug Chloroquine. Didesethyl c
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Bioactivity Didesethyl chloroquine (Bisdesethylchloroquine) is a major metabolite of the antimalarial drug Chloroquine. Didesethyl chloroquine is a potent myocardial depressant[1][2].
Name Didesethyl chloroquine
CAS 4298-14-0
Formula C14H18ClN3
Molar Mass 263.77
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Biot C, et al. Synthesis and antimalarial activity in vitro of potential metabolites of ferrochloroquine and related compounds. Bioorg Med Chem. 1999 Dec;7(12):2843-7. [2]. Essien EE, et al. Effects of chloroquine and didesethylchloroquine on rabbit myocardium and mitochondria. J Pharm Pharmacol. 1986 Jul;38(7):543-6.