Bioactivity | Dichlorphenamide (Diclofenamide) is an orally active, specific, carbonic anhydrase inhibitor. Dichlorphenamide can reduce intraocular pressure by inhibiting the secretion of water from the eye. Dichlorphenamide can be used for glaucoma research[1]. | ||||||||||||
In Vivo | Dichlorphenamide can reduce IOP locally in male albino rabbits[1]. Animal Model: | ||||||||||||
Name | Dichlorphenamide | ||||||||||||
CAS | 120-97-8 | ||||||||||||
Formula | C6H6Cl2N2O4S2 | ||||||||||||
Molar Mass | 305.16 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Kanski, J.J., Carbonic anhydrase inhibitors and osmotic agents in glaucoma. Carbonic anhydrase inhibitors. Br J Ophthalmol, 1968. 52(8): p. 642-3. [2]. Rucquoy, M. and L. Sorel, Diclofenamide in the treatment of therapy-resistant epilepsy. Acta Neurol Belg, 1978. 78(3): p. 174-82. |