| Bioactivity | Dexamethasone (Hexadecadrol) (GMP) is Dexamethasone (HY-14648) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Dexamethasone is an agonist of glucocorticoid receptor[1][2][3][4]. |
| Invitro | Dexamethasone (GMP) (100 nM; 10 d) increases myotubes formation and cytoplasmic lipid droplets accumulation of RCJ 3.1 cells[1].Dexamethasone (GMP) (10 nM-1 μM; 0-6 d) induces osteogenesis of chick periosteum cells with an optimal concentration of 100 nM[2].Dexamethasone (GMP) (10 μM) induces osteoblastic differentiation[3].Dexamethasone (GMP) (10 nM) stimulates differentiation of odontoblast-like cells[4]. |
| Name | Dexamethasone (GMP) |
| CAS | 50-02-2 |
| Formula | C22H29FO5 |
| Molar Mass | 392.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Grigoriadis AE, et al. Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bone-derived clonal cell population: effect of dexamethasone. J Cell Biol. 1988 Jun;106(6):2139-51. [2]. Tenenbaum HC, Heersche JN. Dexamethasone stimulates osteogenesis in chick periosteum in vitro. Endocrinology. 1985 Nov;117(5):2211-7. [3]. Rickard DJ, et al. Induction of rapid osteoblast differentiation in rat bone marrow stromal cell cultures by dexamethasone and BMP-2. Dev Biol. 1994 Jan;161(1):218-28. [4]. Alliot-Licht B, et al. Dexamethasone stimulates differentiation of odontoblast-like cells in human dental pulp cultures. Cell Tissue Res. 2005 Sep;321(3):391-400. |
Dexamethasone (GMP)
CAS: 50-02-2 F: C22H29FO5 W: 392.46
Dexamethasone (Hexadecadrol) (GMP) is Dexamethasone (HY-14648) produced by using GMP guidelines. GMP small molecules wor
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