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DL-β-Hydroxybutyryl coenzyme A lithium

CAS: 103404-51-9 F: C25H42Li3N7O18P3S W: 874.45

DL-β-Hydroxybutyryl coenzyme A lithium is an intermediate in the fermentation of butyric acid and the metabolism of lys
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Bioactivity DL-β-Hydroxybutyryl coenzyme A lithium is an intermediate in the fermentation of butyric acid and the metabolism of lysine and tryptophan, and is produced from β-hydroxybutyric acid by short-chain-CoA synthase[1][2].
Invitro DL-β-Hydroxybutyryl coenzyme A lithium (β-Hydroxybutyryl-CoA) can be produced as an intermediate metabolite via the mitochondrial pathway, where impaired mitochondrial function in cancer cells leads to the accumulation of it. At the same time, DL-β-Hydroxybutyryl coenzyme A lithium can also be produced via the fatty acid β-oxidation, which is accelerated by starvation and fasting, leading to the accumulation of it and thus to diseases caused by certain metabolic adaptations[1]. DL-β-Hydroxybutyryl coenzyme A lithium (β-Hydroxybutyryl-CoA) can act as a cofactor for lysine β-hydroxybutyrylation (Kbhb), with elevated levels of histone Kbhb in a streptozotocin (STZ)-induced type 1 diabetes mellitus (T1DM) mouse model[2].
Name DL-β-Hydroxybutyryl coenzyme A lithium
CAS 103404-51-9
Formula C25H42Li3N7O18P3S
Molar Mass 874.45
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.