| Bioactivity | D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement[1]. | ||||||||||||
| Invitro | Chemically, D-Sorbitol (Sorbitol) can be produced from glucose or sucrose, by hydrogenation at high temperature. D-Sorbitol (Sorbitol) can also be produced by bacteria such as Zymomonas mobilis and Candida boidini, by an enzymatic process[1].D-Sorbitol (Sorbitol) is used as a fast disintegrant in capsules and plasticizer in capsule shells and tablet film coatings. In oral liquids, D-Sorbitol (Sorbitol) is used as a sugar substitute and as a drug stabilizer. D-Sorbitol (Sorbitol) is also used as a solubility enhancer for drugs such as indomethacin. D-Sorbitol (Sorbitol) is commonly used as a stabilizing excipient and/or isotonicity agent in both liquid and lyophilized parenteral protein formulations. D-Sorbitol (Sorbitol) is used in topical formulations as a humectant[1]. | ||||||||||||
| Name | D-Sorbitol | ||||||||||||
| CAS | 50-70-4 | ||||||||||||
| Formula | C6H14O6 | ||||||||||||
| Molar Mass | 182.17 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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