Bioactivity | D-Phenothrin ((-)-trans-Phenothrin), an orally active Type II synthetic pyrethroid, is widely used to kill insects, mosquitoes, and human lice. D-Phenothrin is also used in veterinary medicine to control insect pests on animals and protect agricultural crops[1]. |
In Vivo | D-Phenothrin ((-)-trans-Phenothrin; 25-200 mg/kg; IP; 14 consecutive days) significantly, dose-dependently increases oxidative DNA damage in both organs of animals[1]. D-Phenothrin (100, 300 or 1000 mg/kg/day; p.o.; 3 days) exhibits no potential to cause adverse estrogenic or (anti-)androgenic effects[2]. Animal Model: |
Name | D-Phenothrin |
CAS | 26046-85-5 |
Formula | C23H26O3 |
Molar Mass | 350.45 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Atmaca E, et al. d-Phenothrin-induced oxidative DNA damage in rat liver and kidney determined by HPLC-ECD/DAD. Environ Toxicol. 2015 May;30(5):607-13. [2]. Yamada T, et al. Lack of estrogenic or (anti-)androgenic effects of d-phenothrin in the uterotrophic and Hershberger assays. Toxicology. 2003 Apr 22;186(3):227-39. |