| Bioactivity | Cystamine is the disulfide form of the free thiol, cysteamine. Cystamine is an orally active transglutaminase (Tgase) inhibitor. Cystamine also has inhibition activity for caspase-3 with an IC50 value of 23.6 μM. Cystamine can be used for the research of severals diseases including Huntington's disease (HD) [1][2][3]. | |||||||||
| Invitro | Cystamine has inhibition activity for caspase-3 with an IC50 value of 23.6 μM[1].Cystamine (0-500 μM; 0-16 h) inhibits recombinant active caspase-3 in a concentration-dependent manner[1]. Cystamine (250 μM; 10 h) robustly increases the levels of glutathione[1]. Western Blot Analysis[1] Cell Line: | |||||||||
| Name | Cystamine | |||||||||
| CAS | 51-85-4 | |||||||||
| Formula | C4H12N2S2 | |||||||||
| Molar Mass | 152.28 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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