Bioactivity | Cyclopenthiazide is a benzothiadiazine diuretic with antihypertensive properties. Cyclopenthiazide exerts a diuretic effect by inhibiting the reabsorption of sodium chloride and water at the distal renal tubules. Cyclopenthiazide increases the excretory capacity of the rat kidney[1]. |
In Vivo | Cyclopenthiazide (0.5 mg/kg; i.p.; daily, for 3 days; female Wistar rats) increases the excretion of p-aminohippurate (PAH) [1]. Animal Model: |
Name | Cyclopenthiazide |
CAS | 742-20-1 |
Formula | C13H18ClN3O4S2 |
Molar Mass | 379.88 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Bräunlich H. Postnatal development of kidney function in rats receiving thyroid hormones. Exp Clin Endocrinol. 1984 May;83(3):243-50. |