Bioactivity | Cu (II) Protoporphyrin IX is used as a negative control for Zn (II) Protoporphyrin (an inihibitor of heme oxygenase). Heme oxygenase has been implicated in tumor cell resistance to chemotherapy, reduction of free radical formation and inflammation, and associated with vascular repair[1][2][3]. |
Name | Cu(II) protoporphyrin IX |
CAS | 14494-37-2 |
Formula | C34H32CuN4O4 |
Molar Mass | 624.19 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Jozkowicz A, et al. Heme oxygenase-1 in tumors: is it a false friend?. Antioxid Redox Signal. 2007;9(12):2099-2117. [2]. Abraham NG, et al. Heme oxygenase and the cardiovascular-renal system. Free Radic Biol Med. 2005;39(1):1-25. [3]. Kim DH, et al. Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesenchymal stem cells. J Pharmacol Exp Ther. 200 |