Bioactivity | Chrysamine G, a carboxylic acid analogue of Congo Red, can be used as a probe of amyloid deposition in Alzheimer's disease. Chrysamine G also can inhibit Aβ-induced toxicity in PC12 cells[1][2]. |
Name | Chrysamine G |
CAS | 6472-91-9 |
Formula | C26H16N4Na2O6 |
Molar Mass | 526.41 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Klunk WE, et, al. Chrysamine-G binding to Alzheimer and control brain: autopsy study of a new amyloid probe. Neurobiol Aging. Jul-Aug 1995;16(4):541-8. [2]. Klunk WE, et, al. Chrysamine-G, a lipophilic analogue of Congo red, inhibits A beta-induced toxicity in PC12 cells. Life Sci. 1998;63(20):1807-14. |