PeptideDB

Cholic acid sodium

CAS: 361-09-1 F: C24H39NaO5 W: 430.55

Cholic acid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It
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Bioactivity Cholic acid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid sodium is orally active[1][2].
Invitro Cholic acid (1 mg/mL, 30 min) competitively binds Na+/taurocholate cotransporting polypeptide (NTCP) on HepG2 cells and significantly inhibits the uptake of Cholic acid (CA)-nanoliposomes (LPs)-Doxorubicin (DOX)-HCl, which indicates that CA-LPs-DOX-HCl are also uptaken via NTCP-mediated endocytosis pathway[1].
Name Cholic acid sodium
CAS 361-09-1
Formula C24H39NaO5
Molar Mass 430.55
Transport Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)