| Bioactivity | Cholesterol hemisuccinate Tris salt (CHS-Tris) is often used to replace cholesterol in protein crystallography, biochemical studies of proteins, and pharmacology. CHS-Tris and Lauryl Maltose Neopentyl Glycol (LMNG) or n-Dodecyl-β-D-Maltoside (DDM) are used together for the solubilization of membrane proteins while maintaining structural integrity and activity. Cholesteryl succinate also reportedly exhibits antiproliferative activity. |
| CAS | 102601-49-0 |
| Formula | C35H61NO7 |
| Molar Mass | 607.86 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ray SD, et al. Protection of acetaminophen-induced hepatocellular apoptosis and necrosis by cholesteryl hemisuccinate pretreatment. J Pharmacol Exp Ther. 1996 Dec;279(3):1470-83. [2]. Varshosaz J, et al. Folated synperonic-cholesteryl hemisuccinate polymeric micelles for the targeted delivery of docetaxel in melanoma. Biomed Res Int. 2015;2015:746093. |
Cholesterol hemisuccinate Tris salt
CAS: 102601-49-0 F: C35H61NO7 W: 607.86
Cholesterol hemisuccinate Tris salt (CHS-Tris) is often used to replace cholesterol in protein crystallography, biochemi
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