Bioactivity | Cholecystokinin-33 free acid is an analogue of Cholecystokinin (HY-P2932). C-terminal amidation is important for binding of Cholecystokinin to its receptors, and removing the amide group would decrease Cholecystokinin activity. Cholecystokinin-33 free acid can be used to study C-terminal amidation of Cholecystokinin-33[1]. | ||||||
Name | Cholecystokinin-33 free acid | ||||||
Sequence | Lys-Ala-Pro-Ser-Gly-Arg-Met-Ser-Ile-Val-Lys-Asn-Leu-Gln-Asn-Leu-Asp-Pro-Ser-His-Arg-Ile-Ser-Asp-Arg-Asp-{Tyr(SO3H)}-Met-Gly-Trp-Met-Asp-Phe | ||||||
Shortening | KAPSGRMSIVKNLQNLDPSHRISDRD-{Tyr(SO3H)}-MGWMDF | ||||||
Formula | C167H262N50O53S4 | ||||||
Molar Mass | 3946.43 | ||||||
Appearance | 固体 | ||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||
Storage | Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
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Reference | [1]. Chandra, Rashmi, and Liddle, Rodger A. Regulation of Pancreatic Secretion. Pancreapedia: Exocrine Pancreas Knowledge Base. 2020. |