Chlorfenapyr_product_DataBase

Bioactivity

Chlorfenapyr is a pyrrole insecticide. Chlorfenapyr has a mode of action: the mixed function oxidase oxidizes and removes the Nethoxymethyl group to form the active metabolite, CL 303268. Chlorfenapyr is used for termite control and crop protection against a variety of insect and mite pests[1][2].

Invitro

Chlorfenapyr 是一种杀虫剂前体，通过混合功能氧化酶氧化去除 Chlorfenapyr 的 N-乙氧基甲基会产生一种毒性形式，鉴定为 CL 303268，其作用是解偶联线粒体中的氧化磷酸化，导致 ATP 产生中断和能量损失导致细胞功能障碍和随后的生物体死亡。Chlorfenapyr 对哺乳动物的毒性较低[2]。

Name

Chlorfenapyr

CAS

122453-73-0

Formula

C15H11BrClF3N2O

Molar Mass

407.61

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Byung Hyun Baek, et al. Chlorfenapyr-Induced Toxic Leukoencephalopathy with Radiologic Reversibility: A Case Report and Literature Review. Korean J Radiol. 2016 Mar-Apr;17(2):277-80. [2]. Kamaraju Raghavendra, et al. Chlorfenapyr: a new insecticide with novel mode of action can control pyrethroid resistant malaria vectors. Malar J. 2011 Jan 25;10:16.

PeptideDB

Chlorfenapyr

CAS: 122453-73-0 F: C15H11BrClF3N2O W: 407.61