| Bioactivity | Chktide is a substrate for CHK1 and CHK2. Chktide can be used in kinase assays[1][2]. |
| Name | Chktide |
| CAS | 289652-77-3 |
| Sequence | Lys-Lys-Lys-Val-Ser-Arg-Ser-Gly-Leu-Tyr-Arg-Ser-Pro-Ser-Met-Pro-Glu-Asn-Leu-Asn-Arg-Pro-Arg |
| Shortening | KKKVSRSGLYRSPSMPENLNRPR |
| Formula | C115H198N40O33S |
| Molar Mass | 2701.12 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Walker M, et, al. Chk1 C-terminal regulatory phosphorylation mediates checkpoint activation by de-repression of Chk1 catalytic activity. Oncogene. 2009 Jun 18;28(24):2314-23. [2]. Bjørling-Poulsen M, et, al. The 'regulatory' beta-subunit of protein kinase CK2 negatively influences p53-mediated allosteric effects on Chk2 activation. Oncogene. 2005 Sep 8;24(40):6194-200. |