PeptideDB

Cardamonin

CAS: 18956-16-6 F: C16H14O4 W: 270.28

Cardamonin can be found from cardamom, and target various signaling molecules, transcriptional factors, cytokines and en
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Bioactivity Cardamonin can be found from cardamom, and target various signaling molecules, transcriptional factors, cytokines and enzymes. Cardamonin can inhibit mTOR, NF-κB, Akt, STAT3, Wnt/β-catenin and COX-2. Cardamonin shows anticancer, anti-inflammatory, antimicrobial and antidiabetic activities[1][2].
Invitro Cardamonin (5-40 μM, 24 or 48 h) treatment inhibits gastric cancer cell growth[3].Cardamonin (10-30 μM, 24 or 48 h) treatment can regulate the expression of apoptosis relative protein[3].Cardamonin (10-30 μM, 24 or 48 h) treatment can inhibit STAT3 phosphorylation[3].Cardamonin (0-100 μM, 24 h) treatment improves the anti-oxidative capacity in HL-1 cells[4]. Cell Viability Assay[3] Cell Line:
Name Cardamonin
CAS 18956-16-6
Formula C16H14O4
Molar Mass 270.28
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month