| Bioactivity | Capuride is an orally active sedative agent. Capuride has anticonvulsant activity[1]. |
| In Vivo | Capuride (VPA, 38-107 mg/kg p.o.) shows anticonvulsant activity in MES and scMet induced seizures rats[2].Capuride (p.o., rats) shows neurotoxicity with an ED50 of 232 mg/kg[2].Capuride (49-71 mg/kg, i.p.) shows anticonvulsant activity in 6 Hz Psychomotor seizure mice[2]. Animal Model: |
| Name | Capuride |
| CAS | 5579-13-5 |
| Formula | C9H18N2O2 |
| Molar Mass | 186.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Goldstein L, et al. Quantitative EEG analysis of single-dose effect relationships in normal volunteers of Pacinox (capuride), a new antianxiety drug. Biological psychiatry, 1971, 3(2): 165-172. [2]. Jakob Avi Shimshoni, et al. Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid. J Med Chem. 2007 Dec 13;50(25):6419-27. |