| Bioactivity | CPP9 TFA is a small, amphipathic, cyclic cell penetrating peptide (CPP). CPPs bind directly to the plasma membrane phospholipids and enter mammalian cells via endocytosis, followed by efficient release from the endosome. CPP9 TFA can be used for intracellular delivery of therapeutic agents and chemical probes[1]. | ||||||
| Sequence | Cyclo({d-Phe}-{2-Nal}-Arg-{d-Arg}-Arg-{d-Arg}-Gln) | ||||||
| Shortening | Cyclo({d-Phe}-{2-Nal}-R-{d-Arg}-R-{d-Arg}-Q) | ||||||
| Formula | C59H80F12N20O16 | ||||||
| Molar Mass | 1553.37 | ||||||
| Appearance | 固体 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
||||||
| Reference | [1]. Qian Z, et al. Discovery and Mechanism of Highly Efficient Cyclic Cell-Penetrating Peptides. Biochemistry. 2016 May 10;55(18):2601-12. |