| Bioactivity | CLR1501, a fluorescently labeled CLR1404 analog, is a cancer cell-selective fluorescence compound[1][2]. Storage: protect from light. |
| Invitro | CLR1501 exhibits five- to ninefold preferential uptake in these cancer cell lines in vitro compared to normal fibroblasts[1].Excitation/emission peaks are 500/517 nm for CLR1501. CLR1501 exhibits tumor selectivity in vitro and in vivo for human glioblastoma stem-like (GSC) cell lines and xenografts[2]. |
| Name | CLR1501 |
| CAS | 1250963-36-0 |
| Formula | C38H59BF2N3O4P |
| Molar Mass | 701.67 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Weichert JP, et al. Alkylphosphocholine analogs for broad-spectrum cancer imaging and therapy. Sci Transl Med. 2014 Jun 11;6(240):240ra75. [2]. Swanson KI, et al. Fluorescent cancer-selective alkylphosphocholine analogs for intraoperative glioma detection. Neurosurgery. 2015 Feb;76(2):115-23; discussion 123-4. [3]. Deming DA, Maher ME, Leystra AA, et al. Phospholipid ether analogs for the detection of colorectal tumors. PLoS One. 2014;9(10):e109668. |