| Bioactivity | C6 NBD Glucosylceramide is a glucosylceramide fluorescent derivative (Ex=466 nm, Em=535 nm). C6 NBD Glucosylceramide can be used to study the metabolism and internalization of glucosylceramide and also for the determination of glucosyl ceramide synthase activity[1][2][3]. |
| Name | C6 NBD Glucosylceramide |
| CAS | 94885-03-7 |
| Formula | C36H59N5O11 |
| Molar Mass | 737.88 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kok JW, et al. Salvage of glucosylceramide by recycling after internalization along the pathway of receptor-mediated endocytosis. Proc Natl Acad Sci U S A. 1989 Dec;86(24):9896-900. [2]. Hayashi Y, et al. A sensitive and reproducible assay to measure the activity of glucosylceramide synthase and lactosylceramide synthase using HPLC and fluorescent substrates. Anal Biochem. 2005 Oct 15;345(2):181-6. [3]. di Bartolomeo S, et al. Differential chemosensitizing effect of two glucosylceramide synthase inhibitors in hepatoma cells. Biochem Biophys Res Commun. 2001 Oct 19;288(1):269-74. |