| Bioactivity | Bromperidol (R-11333) possesses antipsychotic activity, with a high affinity for central dopamine receptors D2. Bromperidol can kill Mycobacteria in a synergistic manner with Spectinomycin[1][2]. | ||||||||||||
| In Vivo | Bromperidol antagonises stereotyped behaviour and agitation induced by apomorphine or amphetamine, and inhibits conditioned reactions and learned intracranial self-stimulation in rats[1].Bromperidol antagonises apomorphine-induced emesis and inhibits the conditioned avoidance response in dogs[1]. | ||||||||||||
| Name | Bromperidol | ||||||||||||
| CAS | 10457-90-6 | ||||||||||||
| Formula | C21H23BrFNO2 | ||||||||||||
| Molar Mass | 420.32 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Benfield P, et al. Bromperidol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in psychoses. Drugs. 1988 Jun;35(6):670-84. [2]. Ramón-García S, et al. Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen. Antimicrob Agents Chemother. 2011 Aug;55(8):3861-9. |
Bromperidol
CAS: 10457-90-6 F: C21H23BrFNO2 W: 420.32
Bromperidol (R-11333) possesses antipsychotic activity, with a high affinity for central dopamine receptors D2. Bromperi
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