Biliatresone

CAS: 1801433-90-8 F: C18H16O6 W: 328.32

Biliatresone is a natural toxin isolated from Dysphania glomulifera and D. littoralis. Biliatresone, a 1,2-diaryl-2-prop

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Bioactivity	Biliatresone is a natural toxin isolated from Dysphania glomulifera and D. littoralis. Biliatresone, a 1,2-diaryl-2-propenone class of isoflavonoid, produces extrahepatic biliary atresia in a zebrafish model[1].
Invitro	Biliatresone has a reduction in primary cilia and a dose-dependent decrease in visible microtubules, suggesting that Biliatresone decreases microtubule stability in primary neonatal mouse extrahepatic cholangiocytes[1]. Biliatresone (2 µg/ml; for 24 hours) shows disruption of the spheroid lumen and abnormal cholangiocyte polarity in mouse cholangiocyte[1].
Name	Biliatresone
CAS	1801433-90-8
Formula	C18H16O6
Molar Mass	328.32
Transport	Room temperature in continental US; may vary elsewhere.
Storage	-80°C, stored under nitrogen