Bifenthrin_product_DataBase

Bioactivity	Bifenthrin is a synthetic pyrethroid insecticide. Bifenthrin prolongs the opening time of Nav1.8 sodium channels, leading to membrane depolarization and conductance block in the insect nervous system, thereby disrupting neural function. Bifenthrin was effective in inhibiting A. gambiae (LD50=0.15 ng/mg) and C. quinquefasciatus (LD50=0.16 ng/mg). Bifenthrin has good lethality against susceptible and resistant mosquitoes and is very effective in inhibiting blood sucking and can be developed as a mosquito-removal netting material[1][2].
Invitro	联苯菊酯抑制A. gambiae,/i> 和 C. quinquefasciatus，其 LD50 值分别为 0.15 ng/mg 和 0.16 ng/mg[1].联苯菊酯处理过的滤纸接触到 C. quinquefasciatus 和 A. gambiae 的跗节，分别只需 0.5% 和 0.125% 的浓度，即可导致 100% 的死亡[1].
Name	Bifenthrin
CAS	82657-04-3
Formula	C23H22ClF3O2
Molar Mass	422.87
Appearance	Solid
Transport	Room temperature in continental US; may vary elsewhere.
Storage	4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Reference	[1]. Hougard JM, et al. Bifenthrin: a useful pyrethroid insecticide for treatment of mosquito nets. J Med Entomol. 2002 May;39(3):526-33. [2]. Choi JS, et al. Structure-activity relationships for the action of 11 pyrethroid insecticides on rat Na v 1.8 sodium channels expressed in Xenopus oocytes. Toxicol Appl Pharmacol. 2006 Mar 15;211(3):233-44.

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