PeptideDB

Benzoylhypaconine

CAS: 63238-66-4 F: C31H43NO9 W: 573.67

Benzoylhypaconine (Benzoylhypacoitine) is a monoester Aconitum alkaloid, is the main pharmacologic and toxic component.
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Bioactivity Benzoylhypaconine (Benzoylhypacoitine) is a monoester Aconitum alkaloid, is the main pharmacologic and toxic component[1].
Invitro Aconitum alkaloids have narrow therapeutic indices. Their potential toxicity, which is caused by hyperpolarization and activation of voltage-dependent sodium and calcium channels, can result in fatal cardiac poisoning and neurotoxicity[1].
Name Benzoylhypaconine
CAS 63238-66-4
Formula C31H43NO9
Molar Mass 573.67
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Reference [1]. Song S, et al. Simultaneous quantification and pharmacokinetics of alkaloids in Herba Ephedrae-Radix Aconiti Lateralis extracts. J Anal Toxicol. 2015 Jan-Feb;39(1):58-68. [2]. Zhang YY, Yao YD, Cheng QQ, Huang YF, Zhou H. Establishment of a High Content Image Platform to Measure NF-κB Nuclear Translocation in LPS-Induced RAW264.7 Macrophages for Screening Anti-inflammatory Drug Candidates [published online ahead of print, 2022