Bioactivity | Benzoylhypaconine (Benzoylhypacoitine) is a monoester Aconitum alkaloid, is the main pharmacologic and toxic component[1]. |
Invitro | Aconitum alkaloids have narrow therapeutic indices. Their potential toxicity, which is caused by hyperpolarization and activation of voltage-dependent sodium and calcium channels, can result in fatal cardiac poisoning and neurotoxicity[1]. |
Name | Benzoylhypaconine |
CAS | 63238-66-4 |
Formula | C31H43NO9 |
Molar Mass | 573.67 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
Reference | [1]. Song S, et al. Simultaneous quantification and pharmacokinetics of alkaloids in Herba Ephedrae-Radix Aconiti Lateralis extracts. J Anal Toxicol. 2015 Jan-Feb;39(1):58-68. [2]. Zhang YY, Yao YD, Cheng QQ, Huang YF, Zhou H. Establishment of a High Content Image Platform to Measure NF-κB Nuclear Translocation in LPS-Induced RAW264.7 Macrophages for Screening Anti-inflammatory Drug Candidates [published online ahead of print, 2022 |