| Bioactivity | Benzoctamine hydrochloride (Ba-30803) is a psychoactive agent with anti-anxiety effect. Benzoctamine hydrochloride blocks the central postsynaptic serotonin receptors and decreases 5-HT turnover in the brain[1][2]. |
| In Vivo | Benzoctamine hydrochloride (Ba-30803) inhibits the head twitch reaction induced by L-5-hydroxytryptophan (5-HTP) in mice and by 5-methoxytryptamine (5-MT) in rats pretreated with tranylcypromine. Benzoctamine also antagonizes tryptamine (TRP)-induced clonic convulsions of forepaws in rats [2]. |
| Name | Benzoctamine hydrochloride |
| CAS | 10085-81-1 |
| Formula | C18H20ClN |
| Molar Mass | 285.81 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lippmann W, et al. Effects of benzoctamine and chlordiazepoxide on turnover and uptake of 5-hydroxytryptamine in the brain. Br J Pharmacol. 1974;51(4):571-575. [2]. Przegaliński E, et al. On the central antiserotonin activity of benzoctamine and opipramol. Pol J Pharmacol Pharm. 1978;30(6):781-790. |
Benzoctamine hydrochloride
CAS: 10085-81-1 F: C18H20ClN W: 285.81
Benzoctamine hydrochloride (Ba-30803) is a psychoactive agent with anti-anxiety effect. Benzoctamine hydrochloride block
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