Bioactivity | BCY8234 is a mono-methylauristatin E (MMAE)-free analogue of BT8009. BT8009 is a nectin-4 targeting bicycle toxin conjugate for the treatment of solid tumors. BCY8234 attenuates the response to BT8009[1]. |
CAS | 2922478-12-2 |
Formula | C131H185N35O36S4 |
Molar Mass | 2954.34 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Rigby M, et al. BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors. Mol Cancer Ther. 2022 Dec 2;21(12):1747-1756. |