| Bioactivity | Azithromycin is a macrolide antibiotic useful for the treatment of a number of bacterial infections. | ||||||||||||
| Invitro | Azithromycin (2 μM) augments rhinovirus-induced IFNβ expression in primary bronchial epithelial cells from asthmatics, which is associated with over-expression of RIG-I like receptors and repression of viral replication. Knockdown of MDA5, but not knockdown of RIG-I, diminishes azithromycin (2 μM)-enhanced viral-induced IFNβ expression in asthmatic primary bronchial epithelial cells[1]. Azithromycin specifically reduces MMP-9 mRNA and protein levels without affecting NF-κB in endotoxin-challenged monocytic THP-1 cells[2]. | ||||||||||||
| Name | Azithromycin | ||||||||||||
| CAS | 83905-01-5 | ||||||||||||
| Formula | C38H72N2O12 | ||||||||||||
| Molar Mass | 748.98 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|