Autotaxin modulator 1_product_DataBase

Bioactivity

Autotaxin modulator 1 is an autotaxin (ATX) enzyme inhibitor, extracted from patent WO 2014018881 A1, Compound Example 12b. Autotaxin modulator 1 is expected to be useful for researching demyelination due to injury or disease, as well as for researching proliferative disorders such as cancer[1].

Invitro

Autotaxin, a novel motility-stimulating protein, is a secreted glycoprotein widely present in biological fluids, including blood, cancer ascites, synovial, pleural and cerebrospinal fluids, originally isolated from the supernatant of melanoma cells as an autocrine motility stimulation factor[1].Autotaxin is a member of the ectonucleotide pyrophosphatase/phosphodiesterase family of ectoenzymes (E-NPP) that hydrolyze phosphodiesterase (PDE) bonds of various nucleotides and derivatives[1].

Name

Autotaxin modulator 1

CAS

1548743-69-6

Formula

C28H31F6NO3

Molar Mass

543.54

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Guckian, Kevin, et al. Preparation of naphthalenes and isoquinolines as ATX modulating agents. WO 2014018881 A1.

PeptideDB

Autotaxin modulator 1

CAS: 1548743-69-6 F: C28H31F6NO3 W: 543.54