| Bioactivity | Aquacobalamin is one of the major forms of vitamin B12 isolated from mammalian cells. Aquacobalamin accelerates the oxidation of azo-dye Orange II (HY-N1442) by HSO5- in aqueous solutions. Aquacobalamin binds hydrogen peroxide reversibly to form a cobalt(III) hydroperoxo adduct with a 0.25 mM dissociation constant[1][2][3]. |
| CAS | 13422-52-1 |
| Formula | C62H90CoN13O16P |
| Molar Mass | 1363.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ling Xia, et al. Studies on the formation of glutathionylcobalamin: any free intracellular aquacobalamin is likely to be rapidly and irreversibly converted to glutathionylcobalamin. Inorg Chem. 2004 Oct 18;43(21):6848-57. [2]. Maria Lehene, et al. Adduct of Aquacobalamin with Hydrogen Peroxide. Inorg Chem. 2021 Sep 6;60(17):12681-12684. [3]. Ilia A Dereven'kov, et al. Aquacobalamin Accelerates Orange II Destruction by Peroxymonosulfate via the Transient Formation of Secocorrinoid: A Mechanistic Study. Int J Mol Sci. 2022 Oct 7;23(19):11907. |
Aquacobalamin
CAS: 13422-52-1 F: C62H90CoN13O16P W: 1363.36
Aquacobalamin is one of the major forms of vitamin B12 isolated from mammalian cells. Aquacobalamin accelerates the oxid
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