| Bioactivity | Antiproliferative agent-13 (compound 16c) shows an antiproliferative activity against human A375 cells with an IC50 value of 32.7 nM. Antiproliferative agent-13 can be used for the research of cancer[1]. | ||||||||||||
| Target | IC50: 32.7 nM (A375 cells) | ||||||||||||
| Invitro | Antiproliferative agent-13 (0-10 μM; 72 h) affects proliferation of human A375 melanoma cells[1]. Cell Proliferation Assay[1] Cell Line: | ||||||||||||
| Name | Antiproliferative agent-13 | ||||||||||||
| CAS | 663214-48-0 | ||||||||||||
| Formula | C20H18N2O6 | ||||||||||||
| Molar Mass | 382.37 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Zhang H, et al. Design, synthesis and characterization of potent microtubule inhibitors with dual anti-proliferative and anti-angiogenic activities. Eur J Med Chem. 2018 Sep 5;157:380-396 |
Antiproliferative agent-13
CAS: 663214-48-0 F: C20H18N2O6 W: 382.37
Antiproliferative agent-13 (compound 16c) shows an antiproliferative activity against human A375 cells with an IC50 valu
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