| Bioactivity | Antibacterial agent 132 has anticandidal effects against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258) with MIC90 values of <0.06 μg/mL and 62.50 μg/mL, respectively. Antibacterial agent 132 inhibits aromatase enzyme with an IC50 of 0.047μM[1]. |
| Invitro | Antibacterial agent 132 (compound 4j) has the cytotoxicity against NIH/3T3 healthy cell line (IC50=10 μM)[1]. |
| Name | Antibacterial agent 132 |
| Formula | C20H14ClFN4OS |
| Molar Mass | 412.87 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Asaf Evrim Evren，et al. Investigation of Novel Quinoline-Thiazole Derivatives as Antimicrobial Agents: In Vitro and In Silico Approaches. ACS Omega. 2022 Dec 29;8(1):1410-1429. |
Antibacterial agent 132
CAS: F: C20H14ClFN4OS W: 412.87
Antibacterial agent 132 has anticandidal effects against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258) with MIC
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