| Bioactivity | Antibacterial agent 118 (compound 20) is an antimycobacterial agent. Antibacterial agent 118 shows antibacterial activity against Mtb H37Ra, M. aurum, M. smegmatis, Mtb H37Rv and M. avium with MIC values of 40.7, 10.2, 163.0, 62.5 and 62.5 μM, respectively. Antibacterial agent 118 can be used for the research of tuberculosis[1]. |
| Target | IC50: 68 µM (Hep G2) |
| Invitro | Antibacterial agent 118 (1-1000 µM; 24 h) shows cytotoxicity towards Hep G2 cells[1]. Cell Cytotoxicity Assay[1] Cell Line: |
| Name | Antibacterial agent 118 |
| Formula | C19H21N5O2S |
| Molar Mass | 383.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Juhás M, et al. Design, synthesis and biological evaluation of substituted 3-amino-N-(thiazol-2-yl)pyrazine-2-carboxamides as inhibitors of mycobacterial methionine aminopeptidase 1. Bioorg Chem. 2022 Jan;118:105489. |
Antibacterial agent 118
CAS: F: C19H21N5O2S W: 383.47
Antibacterial agent 118 (compound 20) is an antimycobacterial agent. Antibacterial agent 118 shows antibacterial activit
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.