| Bioactivity | Antibacterial agent 106 (compound 8) is an orally active and potent antibacterial agent with antibiofilm activity. Antibacterial agent 106 shows potent antibacterial effect against multi-drug resistant (MDR)-Gram positive pathogens. Antibacterial agent 106 is highly effective in clearing 99.7% of the intracellular methicillin-resistant S. aureus (MRSA) harbored inside macrophages[1]. |
| In Vivo | Antibacterial agent 106 (compound 8) can penetrate gut cells and reach plasma within 15 min and maintain effective plasma concentration for around 12 h[1]. |
| Name | Antibacterial agent 106 |
| CAS | 2459657-11-3 |
| Formula | C20H24N6S |
| Molar Mass | 380.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hosny Y, et al. Modifying the lipophilic part of phenylthiazole antibiotics to control their drug-likeness. Eur J Med Chem. 2020 Jan 1;185:111830. |
Antibacterial agent 106
CAS: 2459657-11-3 F: C20H24N6S W: 380.51
Antibacterial agent 106 (compound 8) is an orally active and potent antibacterial agent with antibiofilm activity. Antib
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