| Bioactivity | Antazoline (phosphate) is an H1 receptor antagonist that affects the activity of the central nervous system, has a potent antiarrhythmic effect[1][2][3]. |
| Invitro | Antazoline (phosphate) shows good inhibitory effect on HBV DNA in the supernatant of HepAD38 and Huh7 cells with the value of EC50 is 2.910 μmol/L and 2.349 μmol/L, respectively[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Antazoline phosphate 相关抗体: Cell Viability Assay[2] Cell Line: |
| In Vivo | Antazoline (phosphate) (IP; 0.01 ml/g; 30min) as H1 receptor antagonists diminishes the anticonvulsant activity of carbamazepine and diphenylhydantoin[3]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
| CAS | 154-68-7 |
| Formula | C17H22N3O4P |
| Molar Mass | 363.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. MariuszŚwiąder,et al. Influence of antazoline and ketotifen on the anticonvulsant activity of conventional antiepileptics against maximal electroshock in mice. Eur Neuropsychopharmacol. 2004 Aug;14(4):307-18. [2]. Jing Li, et al. Repurposing of Antazoline Hydrochloride as an Inhibitor of Hepatitis B Virus DNA Secretion. Virol Sin. 2021 Jun;36(3):501-509. [3]. Maciej T Wybraniec, et al. Efficacy and safety of antazoline for cardioversion of atrial fibrillation: propensity score matching analysis of a multicenter registry (CANT II Study). Pol Arch Intern Med. 2022 Jun 29;132(6):16234. |
Antazoline phosphate
CAS: 154-68-7 F: C17H22N3O4P W: 363.35
Antazoline (phosphate) is an H1 receptor antagonist that affects the activity of the central nervous system, has a poten
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