| Bioactivity | Ankaflavin, isolated from Monascus-Fermented red rice, is an orally active PPARγ agonist. Ankaflavin exhibits selective cytotoxic effect and induces cell death through apoptosis on cancer cells. Ankaflavin has anti-inflammatory, anti-cancer, antiatherosclerotic, and hypolipidemic effects[1][2]. |
| Invitro | Ankaflavin (0-50 µg/mL, 48 h) shows cytotoxicity against cancer cells with no significant toxicity toward normal cells[1].Ankaflavin (0-30 µg/mL, 0-48 h) arrests Hep G2 cell cycle at sub-G1 phase in a dose- and time-dependent manner[1].Ankaflavin (25 µg/mL, 48 h) induces Hep G2 cell apoptosis[1]. Cell Cytotoxicity Assay[1] Cell Line: |
| Name | Ankaflavin |
| CAS | 50980-32-0 |
| Formula | C23H30O5 |
| Molar Mass | 386.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |