| Bioactivity | Amorolfine (Ro 14-4767/002) hydrochloride is a potent anti-fungal agent. Amorolfine hydrochloride inhibits ergosterol biosynthesis. Amorolfine hydrochloride has the potential for the research of Neoscytalidium dimidiatum onychomycosis[1][2]. |
| Invitro | Amorolfine hydrochloride acts primarily by inhibiting ergosterol biosynthesis, a component of fungal cell membrane, and possesses both fungistatic and fungicidal activity[1].Amorolfine hydrochloride (0-128 mg/l) (2-7 days) shows anti-fungal activity for Dermatophyte fungi, Filamentous fungi, Pathogenic yeasts, Dimorphic fungi, Dematiaceous fungi[1].Amorolfine hydrochloride shows anti-fungal activity with 90% killing corresponding concentrations of 3, 3, 10 and 100 mg/L for Trichophyton mentagrophytes, C. albicans, Histoplasma capsulatum, Cryptococcus neoformans, respectively[1]. |
| Name | Amorolfine hydrochloride |
| CAS | 78613-38-4 |
| Formula | C21H36ClNO |
| Molar Mass | 353.97 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Amorolfine hydrochloride
CAS: 78613-38-4 F: C21H36ClNO W: 353.97
Amorolfine (Ro 14-4767/002) hydrochloride is a potent anti-fungal agent. Amorolfine hydrochloride inhibits ergosterol bi
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