| Bioactivity | Ammonium chloride, as a heteropolar compound with pH value regulation, can cause intracellular alkalization and metabolic acidosis thus effecting enzymatic activity and influencing the process of biological system. Ammonium chloride is an autophagy inhibitor[1][2]. | ||||||||||||
| Invitro | Ammonium chloride (NH4Cl), a lysosomotropic agent that raises intralysosomal pH, reduces the yield of reovirus during infection of mouse L cells[2]. | ||||||||||||
| In Vivo | Ammonium chloride (0.28 M in drinking water) promotes the survival of myocardial cells in vivo by decreasing contractile dysfunction, cardiac hypertrophy, inflammation, apoptosis and autophagy[1]. Animal Model: | ||||||||||||
| Name | Ammonium chloride, AR, 99.5% | ||||||||||||
| CAS | 12125-02-9 | ||||||||||||
| Formula | ClH4N | ||||||||||||
| Molar Mass | 53.49 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Huang X, et al. NH4Cl treatment prevents doxorubicin-induced myocardial dysfunction in vivo. Life Sci. 2019;227:94-100. [2]. Canning WM, Fields BN. Ammonium chloride prevents lytic growth of reovirus and helps to establish persistent infection in mouse L cells. Science. 1983;219(4587):987-988. |
Ammonium chloride, AR, 99.5%
CAS: 12125-02-9 F: ClH4N W: 53.49
Ammonium chloride, as a heteropolar compound with pH value regulation, can cause intracellular alkalization and metaboli
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