| Bioactivity | Alizapride is a potent antiemetic, acting as a dopamine receptor antagonist. Alizapride also used in human digestive disorders[1][3]. |
| Target | Dopamine 2 receptor |
| In Vivo | Alizapride (2.5, 5, 10, 25 μg/kg; SC; 7 consecutive days) significantly reduces the bound IgG-sensitized erythrocytes with Splenic macrophages isolated from animals[2]. Animal Model: |
| Name | Alizapride |
| CAS | 59338-93-1 |
| Formula | C16H21N5O2 |
| Molar Mass | 315.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. P L Warzee, et al. Manometric study of the activity of alizapride on the motor function of the human sphincter of Oddi. J Clin Pharm Ther. 1988 Aug;13(4):281-4. [2]. Gomez, et al. Macrophage Fcgamma receptors expression is altered by treatment with dopaminergic drugs. Clinical immunology (Orlando, Fla.) vol. 90,3 (1999): 375-87. [3]. Seng, et al. Anti-emetic effect of high-dose metoclopramide vs alizapride--a randomised crossover study. British journal of clinical pharmacology vol. 38,3 (1994): 282-4. |
Alizapride
CAS: 59338-93-1 F: C16H21N5O2 W: 315.37
Alizapride is a potent antiemetic, acting as a dopamine receptor antagonist. Alizapride also used in human digestive dis
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