PeptideDB

Alizapride hydrochloride

CAS: 59338-87-3 F: C16H22ClN5O2 W: 351.83

Alizapride is a potent antiemetic, acting as a dopamine receptor antagonist. Alizapride also used in human digestive dis
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Bioactivity Alizapride is a potent antiemetic, acting as a dopamine receptor antagonist. Alizapride also used in human digestive disorders[1][3].
Target Dopamine receptor
In Vivo Alizapride (2.5, 5, 10, 25 μg/kg; SC; 7 consecutive days) significantly reduces the bound IgG-sensitized erythrocytes with Splenic macrophages isolated from animals[2]. Animal Model:
Name Alizapride hydrochloride
CAS 59338-87-3
Formula C16H22ClN5O2
Molar Mass 351.83
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Reference [1]. Bleiberg H, et al. Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial. Cancer Chemother Pharmacol. 1988;22(4):316-20.