| Bioactivity | Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs)[1][3]. |
| Invitro | Adipokinetic hormone II (Locusta migratoria) (radiolabeled; 1 pmol in 10 μL of 10% methanol; 30 min on ice, and repeated for 2 h at 30 ℃) shows no association with one of the larger protein components, indicating a lack of separate transporting or carrier protein in the hemolymph[1].Adipokinetic hormones (AKHs) are known to be involved in insect immunity and shows the mechanism of metabolic stimulation, leading a significant increase in carbon dioxide production, and efficacy increase of toxins produced by I. fumosorosea in the cockroach's body[2].Adipokinetic hormone II is more effective than hormone I in bringing about an accumulation of cAMP in the fat body[4]. |
| Name | Adipokinetic hormone II (Locusta migratoria) |
| CAS | 98968-94-6 |
| Formula | C43H57N11O11 |
| Molar Mass | 903.98 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |