| Bioactivity | Abanoquil (U-K52046), an potent and selective α-1 adrenoceptor antagonist, is an anti-arrhythmic agent. Abanoquil can be used for erectile dysfunction research[1][2]. | ||||||||||||
| In Vivo | Abanoquil 在猴子模型体内注射时能够松弛收缩的组织条并诱导勃起反应[1]。 | ||||||||||||
| Name | Abanoquil | ||||||||||||
| CAS | 90402-40-7 | ||||||||||||
| Formula | C22H25N3O4 | ||||||||||||
| Molar Mass | 395.45 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. A Giraldi, et al. Abanoquil, a new alpha-1 adrenoceptor antagonist. In vitro and in vivo effect on erectile tissue. Int J Impot Res. 2000 Mar;12(S1):S37-S40. [2]. T C Tham, et al. Dose-dependent alpha 1-adrenoceptor antagonist activity of the anti-arrhythmic drug, abanoquil (UK-52,046), without reduction in blood pressure in man. Br J Clin Pharmacol. 1992 Apr;33(4):405-9. |